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Author

Pei-Lai Liu

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Open access Oct 2026

Sinensetin ameliorates osteoarthritis progression by modulating the NF-κB/NLRP3 signaling pathway and suppressing chondrocyte pyroptosis.

Sinensetin (SIN) is a natural flavonoid with potential anti‑inflammatory effects. This study investigated whether SIN ameliorates osteoarthritis (OA) and explored its underlying mechanisms. In vitro, SIN (0.05-1 μg/mL) protected human OA chondrocytes from IL‑1β‑induced viability loss. Transcriptome sequencing and molec...

Zhen-Dong Liu, Rui-Zhou Liu, Hong-Wei Yue et al. · 0 citations
Sep 2026

An Artificial Intelligence-Based Preoperative Planning System for High Tibial Osteotomy Significantly Enhances Planning Speed With Comparable Accuracy to Surgeons.

PURPOSE To develop an artificial intelligence-based system capable of measuring preoperative alignment parameters, calculating correction angles, and visualizing outcomes for open wedge high tibial osteotomy (OWHTO) and to validate the accuracy and efficiency of the system in clinical cases. METHODS Between January a...

Song-Lin Li, Zhe Li, Hong-Kai Zhang et al. · 0 citations

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