Pei-Hsuan Chen

Reactive oxygen species-dependent regulation of hypoxia-inducible factor 1α/C-X-C motif chemokine receptor 4 signaling promotes ozone-induced cancer metastasis.

Air pollutants, including vehicle emissions and photochemical smog such as ozone, have become a significant health concern in most industrialized nations. Inhaling ozone has repeatedly been linked to increased lung inflammation, immune responses, and cancer development, ultimately speeding up lung cancer metastasis and...