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Author

Paulo Kassab

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Open access Oct 2026

Induced mismatch repair deficiency: a hypothesis for the transient and reversible sensitization of mismatch repair-proficient tumors to Immune checkpoint blockade

Immune checkpoint blockade (ICB) has transformed the treatment landscape of multiple malignancies, producing durable responses and long-term survival in subsets of patients with advanced cancer. However, the clinical benefit of ICB remains largely restricted to tumors displaying pre-existing immune activation, high tum...

P. Assumpção, A. Leal, W. Barra et al. · 0 citations
Open access Aug 2026

Clinicopathological features, morbidity and survival in gastric adenocarcinoma, with a focus on stage III: a retrospective institutional cohort analysis

Stage III gastric adenocarcinoma demonstrates marked clinicopathological heterogeneity, which directly impacts morbidity, mortality, and survival, and lymph node involvement is a relevant prognostic determinant.

Mariana Freire Pinto, Paulo Kassab, O. Castro et al. · 0 citations

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