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Paul K. Crane

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Open access Nov 2026

Topographic reference modelling of white matter hyperintensities across the adult lifespan

White matter hyperintensities (WMH) are among the most common MRI findings in older adults. They are widely regarded as markers of brain aging and cerebral small-vessel disease, and associated with risk for cognitive decline, Alzheimer’s disease and related dementias (ADRD), and stroke. White matter hyperintensities (W...

M. Alshikho, J. Pyne, Natalie C. Edwards et al. · 0 citations

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