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Paul C. Willems

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Open access Sep 2026

Reference prices matter: impact on cost analyses in economic evaluations

Abstract Objectives Variability in methodology and pricing across country-specific health economic evaluation (EE) guidelines hampers cross-national transferability. Guideline updates can also impede generalizability within countries over time. This study empirically illustrates how changes in reference prices impact c...

Thomay-Ayala Hoelen, Ann-Sophie Nebel, Agnes T. G. Paulus et al. · 0 citations

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