Author

Patrick Pirrotte

2 papers indexed here

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Open access Sep 2026

Global mapping of protein localization in vegetative Dictyostelium discoideum by subcellular spatial proteomics

Dictyostelium discoideum is a genetically tractable amoebozoan model organism widely used to study conserved eukaryotic cellular processes, yet a comprehensive map of its subcellular proteome has been lacking. Here, we combined subcellular fractionation with label-free mass spectrometry to resolve a global protein loca...

Statton Tinker, Yu-Ping Poh, Katarzyna Dąbrowska et al. · bioRxiv · 0 citations

Open access Jul 2026

Extracellular vesicles from cytokine-treated human pancreatic ductal cells enhance HLA class I expression in beta cells

Exposure of T1D-associated cytokines to primary human ductal cells altered cargo of secreted EVs, suggesting a previously unknown ductal cell communication pathway with a potential implication for modulating beta cells during T1D progression.

Neslihan Erdem, H. Zook, Janine C. Quijano et al. · Frontiers in Immunology · 0 citations