Author

Patricia Hedenqvist

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Open access Aug 2026

A hydroxyapatite-based synthetic bone graft reduces intervertebral motion at 12 months, as measured by CT-RSA, in a porcine model of ACDF

Introduction Pseudarthrosis remains a significant complication after anterior cervical discectomy and fusion (ACDF), often causing revision surgery. Synthetic bone grafts (SBGs) offer an alternative to autografts, but objective methods for assessing intervertebral motion (IVM) are needed. Computed tomography-based radi...

Maria Östman, P. Försth, O. Sandberg et al. · Brain and Spine · 0 citations

Open access Jul 2026

Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis.

Myocardial ischemia-reperfusion (MIR) injury drives adverse remodeling and heart failure after ST-elevation myocardial infarction (STEMI), yet no therapy directly targets the fibrotic response. Here, we developed a good manufacturing practice-compatible extracellular vesicle (EV)-enriched secretome from bone marrow mes...

Karl-Henrik Grinnemo, Ken Braesch-Andersen, Johan O. Wedin et al. · Cell Stem Cell · 1 citation