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Author

Pathum Kossinna

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Open access Sep 2026

Prefibrotic bone marrow microenvironment is a hallmark of clonal hematopoiesis

F fibro-inflammatory BM remodeling is established as a defining feature of clonal hematopoiesis of indeterminate potential, linking it to prefibrotic stromal changes and niche reorganization that may facilitate progression to overt malignancy.

Alicia G. Aguilar-Navarro, Gibran Edun, M. Gower et al. · 1 citation
Open access Aug 2026

IBAS: Interaction-bridged association studies discovering novel genes underlying complex traits

Interaction-Bridged Association Study is introduced, a general framework that incorporates pathway-level interaction patterns into genotype–phenotype association analysis without explicitly enumerating interactions, and provides a statistically robust and computationally tractable framework for incorporating interactio...

Dinghao Wang, Pathum Kossinna, Karen Ardila et al. · 0 citations

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