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Author

Pasquale Parisi

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Review Open access Sep 2026

The bidirectional relationship between epilepsy and sleep: a narrative review

A multidisciplinary approach integrating systematic screening for sleep disorders, optimization of antiseizure medication timing and selection, treatment of comorbid obstructive sleep apnea, and behavioral sleep interventions has the potential to meaningfully improve outcomes in patients with epilepsy.

Giulia Bellone, Martina Bonometti, Alice Rubeo et al. · 0 citations
Review Open access Aug 2026

PPP1R21-Related neurodevelopmental disorder: Phenotypic delineation, variant spectrum, and pathophysiological mechanisms

PPP1R21-related neurodevelopmental disorder (PPP1R21-NDD) is an ultra-rare autosomal-recessive encephalopathy caused by dysfunction of the Five-subunit Endosomal Rab5 and RNA/ribosome intermediarY (FERRY) complex. To delineate the clinical, neuroimaging, and molecular spectrum of PPP1R21-NDD and outline diagnostic and...

F. Comisi, G. Di Pasquale, A. Comisi et al. · 0 citations

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