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Parnika Kant

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Open access Aug 2026

Microtubule Lattice Spacing Governs MAP-Motor Regulation

It is found that kinesin-1 is largely insensitive to tubulin PTMs but is strongly regulated by MT lattice spacing, which supports a two-layer transport code in which MT lattice spacing directs MAP binding, and MAPs determine which motors can move along individual MT tracks.

Jonathan Fernandes, Joseph Slivka, Aryan Taheri et al. · 0 citations

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