MoSPR: Histology-to-Gene Expression Prediction with Morpho-Spatial Macrostates and Low-Rank Molecular Programs
MoSPR (Morpho-Spatial Program Regression), a linear framework that couples an adjacency-informed histology representation with a low-rank molecular basis, provides an interpretable link between spatially coherent macrostate regions and their associated molecular programs.
Dongmyung Shin, Geong-Ran Lee, Yesung Cho et al.
· 0 citations