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Author

Panagiotis Tsakiroglou

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Open access Aug 2026

Targeting EZH2 Oncogenic Splicing: Decoding the Regulatory Network and Antisense Correction

This study instigated a gene-specific targeted strategy by unlocking the regulatory network, and designed antisense oligonucleotides (ASOs) targeting important regulatory sites, demonstrating that ASO pharmacology is an actionable strategy for clinical development, challenging the existing paradigms in SF-mutated cancers.

Md Rafikul Islam, Preeti Nagar, Naomi McNaughton et al. · 0 citations

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