Low-frequency centromedian stimulation in patients with generalized or multifocal drug-resistant epilepsy previously submitted to high-frequency stimulation: A prospective study.
OBJECTIVE Drug-resistant epilepsy (DRE) remains a significant clinical challenge, affecting approximately 30% of patients. Deep brain stimulation (DBS) of the centromedian thalamic nucleus (CM) has emerged as a viable therapy for generalized and multifocal seizures. Although high-frequency stimulation (HFS) is the clin...