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Author

Padson Danraharn

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Open access 2026

Amorphous solid dispersion of diosmetin prepared by hot melt extrusion: Processability, stability and dissolution behavior

Diosmetin (DM) is a natural flavonoid with poor water solubility and low bioavailability. This study aimed to improve the dissolution of DM by preparing amorphous solid dispersions (ASDs) using hot melt extrusion (HME) with chitosan lactate (CL) and polyvinylpyrrolidone K30 (PVP-K30). The processability of the formulat...

Padson Danraharn, V. Sareedenchai, Thanu Thongnopkoon · 0 citations

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