Pablo Balado-Simó

Revisiting the Interferon Axis in Systemic and Cutaneous Lupus Erythematosus: From Targeted Therapy to Real-World Clinical Practice

For many years, systemic lupus erythematosus (SLE) pathogenesis was interpreted primarily through the lens of adaptive immunity, with emphasis on disruption of T- and B-cell tolerance, autoantibody production, immune-complex deposition, and complement activation. However, a major shift in the understanding of SLE immun...