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P. Vlachakis

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Review Open access Oct 2026

Non-Invasive Assessment of Coronary Microvascular Dysfunction: From Flow Quantification to Clinical Decision Making

Coronary microvascular dysfunction (CMD) is a major mechanism of myocardial ischemia and adverse cardiovascular outcomes in patients with angina or dyspnea, both in the absence and in the presence of obstructive coronary artery disease. Because the coronary microcirculation cannot be visualized directly with routine an...

Panagiotis Theofilis, A. Sakalidis, Kyriakos Dimitriadis et al. · 0 citations
Review Oct 2026

Post-treatment risks of transcatheter aortic valve implantation: should we be increasing preventative measures?

INTRODUCTION Transcatheter aortic valve implantation (TAVI) has become an established treatment for severe aortic stenosis across an expanding risk spectrum. As indications extend to younger and lower-risk patients, post-treatment complications with implications for survival, quality of life, and valve durability requi...

Panagiotis Theofilis, P. Vlachakis, George Koutsopoulos et al. · 0 citations
Review Open access Sep 2026

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation

Hypertension remains the leading modifiable cause of cardiovascular death, yet fewer than one in four treated adults achieves guideline-recommended blood pressure targets. Catheter-based renal denervation interrupts efferent and afferent renal sympathetic signalling and lowers blood pressure continuously and independen...

Ioannis Skalidis, L. Koliastasis, P. Vlachakis et al. · 0 citations
Review Sep 2026

Complications After Permanent Pacemaker Implantation in Patients with Congenital Complete Atrioventricular Block: A Systematic Review and Meta-analysis.

BACKGROUND Congenital complete atrioventricular block (CCAVB) requires pacing from early life, yet the long-term burden of pacing-induced cardiomyopathy (PICM), mortality, and device-related complications has not been quantitatively synthesized. OBJECTIVE To determine the incidence of PICM, mortality, and device-rela...

P. Vlachakis, Panagiotis Theofilis, Maria Drakopoulou et al. · 0 citations
Review Open access Jul 2026

Multimodality echocardiography in structural heart disease: the evolving role of the interventional imager

This review outlines the expanding role of echocardiography across the spectrum of TSHIs, highlighting the importance of multimodality imaging, including three-dimensional transoesophageal echocardiography (3D TEE), intracardiac echocardiography (ICE) and fusion imaging techniques, for comprehensive structural evaluati...

N. Ktenopoulos, K. Vlasopoulou, P. Vlachakis et al. · 0 citations

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