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Author

P. Verginis

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Open access Sep 2026

Biological sex defines regulatory T-cell reprogramming trajectories in immune-related adverse events and autoimmunity

Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 and CTLA-4 pathways have revolutionized cancer therapy but are frequently associated with immune-related adverse events (irAEs), i.e. inflammatory toxicities that resemble classical autoimmune diseases and reflect disruption of peripheral tolerance. Reg...

G. Kontogianni, P. Kouzis, H. Gogas et al. · 0 citations

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