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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

P. Timpson

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2 papers indexed here

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Sep 2026

Abstract A056: Targeting the mutant p53 cancer cell secretome sensitizes tumors to gemcitabine/nab-paclitaxel chemotherapy and reduces metastasis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal and metastatic malignancy, with standard-of-care treatments, such as gemcitabine/nab-paclitaxel (GnP) offering limited improvement for patients with advanced disease. We and others have shown that co-targeting key factors in combination with chemotherapy...

Shona Ritchie, Victoria M. Tyma, Shanna Hafiz et al. · 0 citations
Sep 2026

Abstract B133: ROCK2 inhibition alters pancreatic cancer fibrosis and decreases metastasis

Pancreatic cancer (PC) is a genetically complex, highly fibrotic, and treatment-refractory malignancy. At the time of clinical diagnosis most patients present with locally advanced, or metastatic disease, which renders them ineligible for surgery and leaves standard-of-care chemotherapy as the predominant treatment....

Niamh E. P. Mills, K. Murphy, Lily M. Channon et al. · 0 citations

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