Open access
Aug 2026
Evaluating the outputs of ARAE-based molecular generative model for synthetic accessibility and BTK inhibition.
This proof-of-concept study evaluated hypothetical drug-like molecules generated by an adversarial regularized autoencoder (ARAE) architecture for their synthetic tractability and inhibitory effects on Bruton's tyrosine kinase (BTK).
Goutham Rajendran, T. Nguyen-Vo, Hunter C. Murray et al.
· Bioorganic & Medicinal Chemi... · 0 citations