Author

P. Seibler

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Open access Sep 2026

Unified long-read panel for Parkinson’s and repeat expansion disorders

Adaptive sampling is a versatile genetic diagnostic tool in neurodegenerative disorders, while enabling cost-effective multiplexing, and further validation and improvements in bioinformatic analysis are needed.

A. Fienemann, J. C. Prietzsche, Joshua Laβ et al. · npj Parkinson's Disease · 0 citations

Open access Jul 2026

Dissecting the transcriptome of Parkin (PRKN)-linked Parkinson’s disease using 2D and 3D hiPSC-neuronal models

This work generates human induced pluripotent stem cell-derived midbrain dopaminergic neurons using both a 2D differentiation protocol and a recently developed 3D method based on the microencapsulation of hiPSCs in small alginate/fibronectin beads.

A. Zanon, E. Kerschbamer, D. Riekschnitz et al. · Communications Biology · 0 citations