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Open access Nov 2026

Optimization and Evaluation of Microsponge-Embedded Thermoresponsive In-Situ Gel for Intranasal Delivery of Sumatriptan Succinate

Migraine is a prevalent neurological disorder requiring rapid and effective therapeutic intervention. However, the conventional oral administration of Sumatriptan succinate (SS) is limited by extensive first-pass metabolism, low bioavailability, and a short biological half-life. This study aimed to develop and optimize...

Sabina Meraj, R. Surve, N. Shivathaya et al. · 0 citations

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