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Review Open access Oct 2026

NEU3 at the Plasma Membrane: Context-Dependent Ganglioside Remodeling in Health and Disease.

Cell-surface gangliosides tune receptor signaling, cell-state transitions, and responses to stress. NEU3 is a mammalian sialidase associated with the plasma membrane and endomembranes that preferentially removes terminal sialic acids from gangliosides. Here, we critically review biochemical studies, cultured-cell exper...

F. Cirillo, P. Rota, Luigi Anastasia et al. · 0 citations

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