Author

P. Rossini

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Sep 2026

APOE-centered transcriptional convergence underlying diverse dementia subtypes.

BackgroundDementia subtypes exhibit diverse clinical and pathological features, yet may share convergent molecular underpinnings. Identifying these common pathways is critical for unified therapeutic strategies.ObjectiveTo delineate the shared genetic architecture and convergent molecular pathways underlying diverse de...

Zhi-Jie Xu, Jie Ma, G. M. Giuffré et al. · Journal of Alzheimer's Disea... · 0 citations

Review Open access Aug 2026

Genetic associations with EEG signatures in mild cognitive impairment: insights into Alzheimer's disease pathophysiology

The convergence of candidate genes on synaptic, neurodevelopmental and neuroinflammatory pathways, and genetically informed clustering linked to plasma p-tau217 and delayed verbal recall, supports the use of EEG-derived endophenotypes for dissecting heterogeneity in early cognitive decline and AD-related pathology.

A. Siitonen, T. Saarinen, M. Liljestrom et al. · medRxiv · 0 citations

Open access Aug 2026

Cognitive components derived from traditional neuropsychological tests and their associations with plasma p-tau217 and p-tau181 in mild cognitive impairment: a multisite analysis.

The findings indicate that a robust four-factor cognitive structure can be identified in clinically defined MCI cohorts without prior biological selection, and the association between latent memory factors and plasma p-tau217, observed primarily in cohorts with higher biomarker burden or clearer amnestic profiles, high...

Ana S. Perez, Hugo L. Hammer, V. Andersson et al. · GeroScience · 0 citations