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Author

P. Prihantono

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Review Open access Sep 2026

CD44 Expression in Head and Neck Cancer: Systematic Review, IHC-based Meta-Analysis, and Pathway Analysis Highlight a Favorable Clinicopathological Association.

Background Head and neck cancer (HNC) is the seventh most common cancer worldwide with its highest incidence in Asia. Tobacco, alcohol, and HPV contribute to this phenomenon. CD44 has been found to have a mechanistic role in tumorigenicity and metastasis, however current literature shows conflicting evidence regarding...

Stella Marleen, M. Cangara, U. Miskad et al. · 0 citations
Open access Aug 2026

Effects of Bauhinia purpurea leaf extracts on cytotoxicity and CCND1 gene expression in MCF-7 cells

Bauhinia purpurea leaf extracts showed solvent-dependent cytotoxicity and downregulated CCND1 gene expression comparable to doxorubicin, highlighting its potential as a phytopharmaceutical for breast cancer therapy via cell cycle inhibition.

Teja Koswara, Rina Masadah, B. Nelwan et al. · 0 citations
Review Open access Sep 2026

CDK4/6 Inhibitors in the Management of Hormone Receptor-Positive (HR+)/Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Advanced Breast Cancer in Indonesia: Challenges, Opportunities, and Recommendations.

A review underscores the critical role of CDK4/6 inhibitors in the treatment of HR+/HER2- ABC, with a particular focus on Indonesian patients, and supports consideration of these agents for inclusion in national clinical guidelines to enhance patient outcomes.

S. S. Panigoro, S. Haryono, P. Prihantono et al. · 0 citations

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