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P. Pei

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Open access Sep 2026

Incidence patterns and genetic validation of primary glaucoma subtypes among 1 million adults in China and the UK.

BACKGROUND/AIMS Primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) are distinct diseases, yet many glaucoma cases in population-based datasets lack subtype specification. We assessed incidence patterns of glaucoma subtypes in China and the UK and used genetic evidence to infer the likely subty...

Charles Li, Bai-Han Wang, R. Walters et al. · 0 citations
Aug 2026

Validation and Comparison of 10-Year Cardiovascular Risk Prediction Models in Two Chinese Prospective Cohorts: The General Population and Patients With Type 2 Diabetes.

BACKGROUND To evaluate and recalibrate commonly used 10-year cardiovascular disease (CVD) risk prediction models in two Chinese cohorts: the general population and adults with type 2 diabetes. METHODS We analysed data from the Wuzhong subcohort of the China Kadoorie Biobank (CKB) and the Jiangsu Biobank for the Preve...

Xikang Fan, Jia-Xi Zhou, Mengxia Li et al. · 0 citations
Open access Sep 2026

Multi-ancestry MHC-pQTL mapping reveals disease-linked HLA protein networks and shared genetic architecture

The major histocompatibility complex (MHC) is one of the most polymorphic and disease-relevant regions of the human genome, yet the downstream effects of MHC variation on circulating protein networks across ancestries remain incompletely defined. Here, we conducted multi-ancestry protein quantitative trait locus (pQTL)...

S. Sarguroh, S. Morris, E. Ng et al. · 0 citations
Review Open access Sep 2026

Associations of long-term exposure to ambient air pollution with fracture risk and bone mineral density: A cohort study of 0.5 million Chinese adults.

BACKGROUND Evidence regarding the effects of air pollution on bone damage remains limited and inconclusive. We aimed to investigate the individual and combined associations of long-term exposure to ambient air pollutants with fracture risk and bone mineral density (BMD). METHODS This study included 490,172 participan...

Hong-Jing Shi, Dong Sun, Xia Meng et al. · 0 citations
Open access Aug 2026

Smoking, Solid Fuel Use for Cooking, and Cancer Mortality: A Prospective Cohort Study in Southwestern China.

Smoking and solid fuel are common exposures among Chinese adults, yet evidence regarding their associations with cancer mortality remains inconsistent, and their joint effects are insufficiently studied. Using data from the Pengzhou site of the China Kadoorie Biobank in Sichuan Province, we applied Cox proportional haz...

Di Wu, Boke Chen, Xiao-Fang Chen et al. · 0 citations
Open access Aug 2026

Adiposity and risk of breast cancer in 280 000 Chinese women: a prospective cohort study

Higher levels of general and central adiposity were associated with a higher risk of breast cancer, in both women who were premenopausal and women who were post-menopausal at baseline in this cohort of Chinese women.

C. Kartsonaki, N. Wright, I. Millwood et al. · 0 citations
Jul 2026

Long-term exposure to air pollution, proteomic aging clocks, and liver-related outcomes in Chinese adults.

Long-term air pollution was associated with higher risks of clinically significant liver-related outcomes and a possible role of proteomic aging in the association between air pollution and liver-related outcomes is suggested, warranting further investigation.

Yating Huang, Dong Sun, Axing Lv et al. · 0 citations
Open access Aug 2026

Responses of growth and quality of Glycyrrhiza uralensis to salt-alkali-tolerant microbial inoculant via the remodeling of rhizosphere microenvironments in moderate and severe saline-alkali soils

The combined application of microbial inoculation and seedling transplanting is recommended for large-scale and high-quality cultivation of G. uralensis in moderately saline-alkali soils of arid northwestern China, as this integrated practice maximizes plant growth, medicinal compound accumulation, and rhizosphere micr...

Qi Guo, Jun Zhang, Xin Li et al. · 0 citations

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