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P. Pausch

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Review Open access Aug 2026

Structural biology of retron-mediated immunity against phage

Abstract Retrons recently emerged as widespread anti-phage systems in which a dedicated reverse transcriptase (RT) produces multicopy single-stranded DNA (msDNA) that regulates associated effector proteins. Once regarded as peculiar retroelements of unknown function, retrons are now understood to operate as modular def...

M. Jasnauskaitė, P. Pausch · 0 citations

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