Open access
Sep 2026
Is there an interaction between hypertension and proteinuria in pediatric chronic kidney disease progression? Evidence from the SP-CKD-Kids cohort.
BACKGROUND Hypertension and proteinuria are established risk factors for chronic kidney disease (CKD) progression in children. Given their pathophysiological interrelationship, whether their coexistence produces a multiplicative interaction remains uncertain. We evaluated this interaction in a Brazilian pediatric cohor...
Ivan Coelho Machado, M. M. Gabriele, L. Prates et al.
· Pediatric nephrology (Berlin... · 0 citations