Author

P. Northcott

3 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Oct 2026

Identification and characterization of a novel distinct Pineal Neoplasm with Neuroendocrine and Epithelial Differentiation (PINNED)

Pineal region tumors are rare neoplasms that occur in all ages and account for less than 1% of all central nervous system (CNS) tumors in adults but are more frequent in children. Here, we describe a previously unrecognized tumor type of pineal origin characterized by a unique and consistent DNA methylation profile tha...

Helena Bode, A. Suwala, B. Gudenas et al. · Acta Neuropathologica · 0 citations

Open access Aug 2026

Cell autonomous regional differences in oligodendrocyte lineage development and responses to oncohistone H3.3 K27M

It is suggested that histone H3.3 K27M mutations drive diffuse midline glioma by ablating intrinsic regional differences in oligodendrocyte development, selectively expanding immature oligodendrocyte precursor cell populations in the brainstem while disrupting normal differentiation programs.

Jared M. Andrews, K. Budd, C. Kwon et al. · Nature Communications · 0 citations

Open access Jul 2026

Circulating tumor DNA precision oncology enables effective and sensitive molecular diagnostics and actionable target detection in pediatric solid tumors - the INFORM experience

By optimizing preanalytical and bioinformatic tools for pediatric settings, this study improved plasma-based cancer detection, molecular tumor characterization, and identification of targetable alterations, laying the groundwork for integration into personalized medicine programs and clinical trials.

K. Maass, P. Puranachot, S. Volz et al. · Genome Medicine · 0 citations