CAR T cells for HLA desensitization: a new era in kidney transplantation
In a recent study published in the New England Journal of Medicine , autologous CD19-and BCMA-directed chimeric antigen receptor (CAR) T-cell therapy was evaluated as a desensitization strategy in two highly sensitized kidney transplant candidates. 1 In this safety run-in cohort of an ongoing phase I clinical trial (NC...