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Open access Sep 2026

Estimated glomerular filtration rate equations and their impact on risk prediction - a tertiary centre experience

In 2021 use of the Kidney Failure Risk Equation (KFRE) was recommended by NICE to guide referrals from primary care. KFRE was developed using the CKD-EPI (2009) equation. We assessed the potential impact of use of multiple different estimating equations for GFR upon KRFE referral thresholds. We searched ou...

Reuben Roy, I. Ali, Sharmilee Rengarajan et al. · 0 citations
Review Open access Sep 2026

Integrating the liver into the cardiovascular-kidney-metabolic syndrome: pathophysiology and therapeutic implications.

PURPOSE OF REVIEW This review examines the mechanistic, epidemiological and therapeutic evidence underpinning liver integration into the cardiovascular-kidney-metabolic (CKM) construct. For the purposes of this review, we use the term cardiovascular-renal-hepatic-metabolic (CRHM) syndrome to denote this expanded framew...

Will R. Marshall, Smeeta Sinha, Darren Green et al. · 0 citations

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