P. Guptasarma

Stationary phase KCl levels trigger changes in Dps conformation to facilitate its partitioning between reversibly-aggregated deposits and Dps-DNA condensates

In E. coli populations subjected to starvation, the transition of cells into stationary-phase is characterized by reduced KCl levels, cytoplasmic acidification, and increased production of Dps, the DNA binding protein from starved cells. Here, we show that at KCl concentrations peculiar to the stationary-phase, Dps dis...