Open access
Oct 2026
Clonally Expanded CD8 T Cells in AML Adopt an NK-Like Program Distinct from Canonical Exhaustion
Y. Chu, Matthew A. Cottam, C. Potts et al.
· bioRxiv · 0 citations
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Open access
Sep 2026
Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms
Rasika Venkataraman, N. Puccio, Tun-Yun Hsueh et al.
· bioRxiv · 0 citations
Open access
Jul 2026
Clonal hematopoiesis is enriched in melanoma and associated with genotype-specific differences in tumor growth and survival
Background The clinical significance of clonal hematopoiesis of indeterminate potential (CHIP) in melanoma remains incompletely defined, particularly with respect to CHIP genotype, clone size, and somatic mutations (e.g BRAF mutations). We integrated human cohort data and a syngeneic melanoma mouse model to evaluate wh...
M. Alford-Holloway, S. Reed, Y. Pershad et al.
· medRxiv · 0 citations