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P. Felgner

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Open access Aug 2026

Comparative characterization of novel lipid nanoparticle adjuvants reveals distinct immunogenicity and reactogenicity profiles

Rational design of adjuvants that simultaneously increase immunogenicity and reduce reactogenicity remains a challenge for protein vaccine development. Conventional adjuvants, like aluminum salts, and oil-in-water emulsions (like MF59, AS03, and AddaVax), work well to increase antibody titers but have variable abilit...

J. Felgner, Jenny E. Hernandez-Davies, Andriy V. Yeromin et al. · 0 citations

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