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Author

P. F. Oliveira

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Open access Oct 2026

Hyperglycemia-induced metabolic rewiring is associated with skeletal muscle loss in a fructose-streptozotocin-induced diabetic rat model.

AIMS This study investigated the impact of hyperglycemia on systemic and skeletal muscle metabolite profiles. METHODS Serum and gastrocnemius metabolites of fructose-fed, streptozotocin-injected rats (T2D) were analyzed by 1H NMR and related to markers of energy metabolism and mitochondrial remodeling. RESULTS T2D...

Alexandra Moreira-Pais, Filipe Oliveira-Brás, Rúben J. Moreira et al. · 0 citations
Jul 2026

Insulin Regulates CD36-Dependent Fatty Acid Uptake but Not Mitochondrial Oxidation in Sertoli Cells.

In the TM4 mouse SC line under defined in vitro conditions, insulin selectively regulates FA uptake while maintaining no control over downstream FA oxidation, revealing that insulin modulates FA entry for storage and/or biosynthesis, while FA oxidation operates constitutively.

M. Llavanera, Ana D Martins, C. Santos et al. · 0 citations

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