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Author

P. Dunaev

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Open access Sep 2026

Re-Evaluating Multi-Kinase Inhibitors Targeting FGFR and VEGFR Pathways for Combined Therapy in Colorectal Cancer: A Preclinical Study

It is shown that receptor tyrosine kinase inhibitors (RTKIs) designed to inhibit the overactivated FGFR and/or VEGFR signaling pathways exert an “off-target” effect on MDR proteins in colorectal cancer (CRC), thereby sensitizing CRC to certain chemotherapies.

S. Boichuk, T. Gessel, P. Dunaev et al. · 0 citations

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