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Review Open access Sep 2026

Person-centred outcomes for integrated care: An AI-supported, multi-method study to develop a novel outcome measure for multiple long-term conditions

Background: The rising prevalence of multiple long-term conditions (MLTC), defined as the co-existence of two or more chronic health conditions within a person, is placing increasing strain on health and care systems as they strive to meet the complex needs of this diverse patient group. People living with multiple lon...

Sarah E. Hughes, Eleanor Hathaway, B. Hughes et al. · 0 citations
Review Open access Aug 2026

Evaluating the use of proactive surveillance and remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): results of a pilot randomised controlled trial.

BACKGROUND The insidious nature of aortic stenosis (AS) combined with the advanced age of the affected population results in underreporting of symptoms and underestimation of impact on functional capacity and quality of life. Although guidelines recommend early valve replacement in severe asymptomatic AS when coupled w...

N. Khan, R. Steeds, Samir Mehta et al. · 1 citation

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