BACKGROUND
Retatrutide is an agonist of GIP, GLP-1, and glucagon receptors, and is currently under investigation for the treatment of obesity, type 2 diabetes, and other comorbidities, including knee osteoarthritis and obstructive sleep apnoea. We aimed to assess the efficacy and safety of retatrutide in adults with ob...
Virginia Bellido, C. L. le Roux, E. Ekinci et al.· The Lancet· 1 citation
KEY POINTS
The cardiovascular-kidney-metabolic (CKM) syndrome framework has important implications in the care of people with kidney diseases. Cardiovascular screening is important in people with kidney diseases, but the approach may differ in this high-risk population. Multiple pharmacotherapies for CKM syndrome offer...
N. Bansal, P. Bjornstad, A. Bress et al.· Journal of the American Soci...· 3 citations
Novel proteins involved in axon guidance, immune response, inflammation, and metabolism associated with LOGC in youth-onset T2D with proteins demonstrating consistent associations across the lifespan and proteomic platforms are identified.
K. Tommerdahl, Kristen R. Miller, Jian-Jun Liu et al.· Journal of Clinical Endocrin...· 0 citations
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