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Author

P. Bhaumik

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Open access Sep 2026

Engineering Glucose-Tolerant Variants by Probing Residues Lining the Active Site of a Fungal β-Glucosidase.

The hydrolytic breakdown of cellobiose into glucose, catalyzed by β-glucosidases, is the last and rate-limiting step in cellulose saccharification for producing fermentable glucose in the bioethanol industry. This limitation arises because β-glucosidase activity is inhibited by factors such as temperature, pH, and gluc...

Barnava Banerjee, Dipayan Chatterjee, Pritha Dasgupta et al. · 0 citations
Aug 2026

Conformational activation of GSK3β by an environmental toxicant suppresses hedgehog signalling and disrupts ciliary homeostasis

It is shown that endosulfan, a banned organochlorine pesticide linked to congenital and reproductive defects, suppresses hedgehog signalling by driving proteolytic processing of GLI transcription factors into repressor forms, establishing a chemical–biological axis through which an environmental toxicant hijacks core k...

Ravikant Piyush, Himani Barmola, A. Bhattacharjya et al. · 0 citations

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