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P. Bakthavatchalam

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Meta-analysis Open access Oct 2026

CagriSema versus Semaglutide 2.4 mg monotherapy for weight management in adults with overweight or obesity, with or without type 2 diabetes: a systematic review, meta-analysis, and trial sequential analysis

Introduction Semaglutide 2.4 mg is the reference pharmacotherapy for weight management, yet many patients do not reach ambitious weight-loss targets. CagriSema, a fixed-dose combination of cagrilintide and semaglutide, may offer additional benefit through complementary mechanisms. We quantified its incremental efficacy...

Zehra Khatoon Rasool, Rajvi K. Shah, Ansharah E. Zinnia Batool et al. · 0 citations
Editorial Open access Aug 2026

The Promise of Blood-Based Biomarkers in Early Detection and Care of Alzheimer’s Disease

BBMs play a crucial role in combating Alzheimer’s disease and should be prioritized, it is essential for governments and health organizations to finance evaluations in varied demographics, establish coverage policies, and integrate BBMs into existing workflows.

Muneeb Khawar, Pugazhandhi Bakthavatchalam · 0 citations
Review Open access Aug 2026

New insights on microglial lysosomal acidification: A therapeutic target of neurodegenerative diseases.

Restoration of microglial lysosomal acidification represents a promising therapeutic strategy for neurodegenerative diseases and a prognostic biomarker for disease progression and therapeutic response.

R. Jaganathan, Srilakshmi Vijayakumar, Yinchi Chen et al. · 0 citations

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