Omics biomarkers of antipsychotic efficacy and safety: focus on lurasidone
Introduction. Lurasidone is an atypical antipsychotic with high affinity for 5-HT₂A, 5-HT₇, and DRD2 receptors; however, its use is limited by interindividual pharmacokinetic variability and dose-dependent adverse effects. Multi-omics approaches offer opportunities for personalized dosing. Objective. To system...