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Organotin-Catalyzed Synthesis, Characterization, Anticancer and Antioxidant Activities, and Molecular Modeling Studies of Nimesulide Ureas as Potential MetAP (Type II) Inhibitors
In silico results and in vitro studies suggest that the nimesulide derivatives may be novel, potential NSAID-based anticancer drug candidates for treating breast, prostate, gastric, and glioblastoma.
Development of Eudragit L100/sodium alginate-carrageenan core/shell nanofiber patches for dermal delivery of omega-3 acid ethyl ester.
Overall, EL100/SA-CRG core-shell nanofibers provide a dry, handleable, and biologically tolerated platform for sustained topical delivery of labile omega-3 ethyl esters, thereby supporting their further development as advanced dermal patches for skin repair and dermocosmetic applications.