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Author

Oscar Moreno

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2 papers indexed here

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Review Open access Sep 2026

Endothelium-targeted and untargeted nanoparticle therapies in thromboinflammatory vascular diseases

Abstract Endothelial cells (ECs) line the vasculature and integrate hemodynamic, inflammatory, and metabolic cues that are crucial in maintaining vascular health. Endothelial dysfunction is a driver of thromboinflammatory conditions including atherosclerosis, thrombosis, stroke, and sepsis-induced multiorgan dysfunctio...

Micheal O. Avoseh, Hua Jin, Oscar Moreno et al. · 0 citations
Open access Sep 2026

Targeting α6β1 Integrin Signaling with Pranlukast to Modulate Venous Endothelium Function and Reduce Post-Thrombotic Vein Wall Injury.

BACKGROUND Post-thrombotic syndrome (PTS) develops in 20-50% of patients following deep vein thrombosis (DVT) due to persistent vein wall injury, inflammation, and fibrotic remodeling. Current anticoagulant therapies do not directly address PTS pathogenesis and carry bleeding risks. We characterized the extracellular m...

Alessia Taylor, Oscar Moreno, Catherine E. Luke Lvt et al. · 0 citations

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