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Author

Omkulthom M. Al Kamaly

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Open access Sep 2026

Holistically benchmarked optimization-assisted green spectrophotometric–chemometric approach for simultaneous determination of piroxicam and venlafaxine in pharmaceutical formulations and spiked human plasma

The recent clinical introduction of the piroxicam (PIR) and venlafaxine hydrochloride (VEN) combination has highlighted the need for analytical methodologies capable of simultaneously quantifying both drugs while minimizing the environmental burden of routine pharmaceutical analysis. To date, only a chromatographic met...

B. Alsfouk, Lateefa A. Al-Khatee, Omkulthom M. Al Kamaly et al. · 0 citations
Sep 2026

Cardioprotective role of vincamine in cyclophosphamide-induced cardiotoxicity through modulation of AMPK/SIRT1, PI3K/Akt, and MAPK pathways.

VIN attenuated changes in the AMPK/SIRT1 and PI3K/Akt axes, MAPK, TLR4/NF-κB p65 signaling, as well as NLRP3-related signaling in a dose-responsive manner, and its cardioprotective effects were accompanied by improved redox balance, increased AMPK/SIRT1 and PI3K/Akt expression, reduced phosphorylated MAPK abundance, an...

Mohammed Tarek Seddek, A. Awad, Marwa E. Elsherbiny et al. · 0 citations

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