Aug 2026
PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia.
Zhendong Cao, Kurtis N. McCannell, Sixiang Yu et al.
· Leukemia · 0 citations
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Open access
Aug 2026
Targeting EZH2 Oncogenic Splicing: Decoding the Regulatory Network and Antisense Correction
This study instigated a gene-specific targeted strategy by unlocking the regulatory network, and designed antisense oligonucleotides (ASOs) targeting important regulatory sites, demonstrating that ASO pharmacology is an actionable strategy for clinical development, challenging the existing paradigms in SF-mutated cancers.
Md Rafikul Islam, Preeti Nagar, Naomi McNaughton et al.
· Genes & Development · 0 citations