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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Olivia Zaleski

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Open access Oct 2026

Chronic XBP1s-mediated activation of the unfolded protein response impairs CD8+ T cell anti-tumor immunity

CD8 + T cells play a crucial role in anti-tumor immunity; however, their functionality is compromised by exhaustion driven by chronic antigen exposure, poor tumor microenvironment, and metabolic dysfunction. Activated CD8 + T cells undergo extensive proteomic remodeling, which includes the induction of the IRE1-X...

Keith A. Nair, Jessica Lee, Olivia Zaleski et al. · 0 citations

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