Author

Ola A. Habotta

2 papers indexed here

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Open access Sep 2026

PLGA-Encapsulated Pterostilbene Mitigates Cadmium-Induced Nephrotoxicity in Rats by Modulating Oxidative Stress, Inflammation, and Apoptosis

Cadmium (Cd) is an environmentally pervasive toxic metal that accumulates in the kidney and promotes oxidative stress, inflammation, and apoptosis. This study evaluated the renoprotective effects of free pterostilbene (PTS) and PLGA-encapsulated PTS (PTS-PLGA) in male Sprague–Dawley rats with Cd-induced nephrotoxicity....

Fahd Alaajam, E. Elmorsy, Amro Duhduh et al. · Toxics · 0 citations

Open access Aug 2026

Liposomal Honokiol Nanoparticles Attenuate Manganese-Induced Hippocampal Neurotoxicity via NRF2/HO-1 and SIRT1/PGC-1α Pathways: Association with Oxidative Stress, Neuroinflammation, Mitochondrial Dysfunction, and Apoptosis

Background/Objectives: Manganese (Mn) is a neurotoxic trace element whose excessive accumulation in the brain can induce hippocampal damage via oxidative stress, mitochondrial dysfunction, neuroinflammation, and apoptosis. This study investigated whether honokiol (HNK) and its liposomal nanoformulation (HNK-LNPs) can a...

Raed AlRuwaili, E. Elmorsy, M. Abdel-Daim et al. · Brain Science · 0 citations