Protective Effects of 2-Chloro-3-Hydrazinylquinoxaline against Doxorubicin-induced Nephrotoxicity via Modulation of Oxidative Stress and Inflammation in Rats
Background: Doxorubicin (DOX) is a widely used anthracycline antibiotic effective against multiple human malignancies, but its clinical utility is limited by well-established nephrotoxicity that frequently manifests as acute kidney injury (AKI). In contrast, the potential nephroprotective effects of 2-chloro-3-hydrazin...