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Author

O. Uysal

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Open access Oct 2026

miR-221/222 Profiles in Small Extracellular Vesicles Derived from Gemcitabine-Sensitive and -Resistant A549 Cancer Stem-Like Cell Spheroids: An In Vitro Study

Background: Gemcitabine is used in the treatment of human non-small cell lung cancer (hNSCLC), yet acquired resistance can limit therapeutic responses. Small extracellular vesicles (sEVs) and microRNAs (miRNAs) have been implicated in chemoresistance-associated intercellular signaling. We profiled the miR-221/222 clust...

Aynaz Ghorbani, O. Uysal, Dilay Karacaoğlu · 0 citations

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