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Review Open access Sep 2026

Targeting the Siglec/sialic-acid axis in glioblastoma: Glycome-mediated immune evasion and emerging therapeutic platforms

Abstract Despite encouraging advances in cancer immunotherapy, several malignancies leverage resistance pathways to escape the effects of treatment. Abnormal cell signaling and cytokine secretion modulated by cancer cells promote a tumor microenvironment (TME), wherein the efficacy of infiltrating immune cells is dimin...

David Lee, William ElNemer, O. Selim et al. · 0 citations
Review Aug 2026

The effects of postoperative neurological deficits on overall survival in patients with malignant peripheral nerve sheath tumors.

In patients undergoing resection for MPNSTs, the development of a permanent postoperative neurological deficit was independently associated with decreased OS, underscoring the importance of balancing maximal oncological resection with preservation of neurological function to optimize long-term outcomes in patients with...

Melanie Alfonzo Horowitz, J. Khalifeh, Xinlan Yang et al. · 0 citations

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