Early Broad-Spectrum Antibiotic Exposure Is Associated with Increased Relapse after Myeloablative TBI-Based Allogeneic Hematopoietic Cell Transplantation.
BACKGROUND Broad-spectrum antibiotics are frequently administered during the peri-transplant period in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). Antibiotic exposure can disrupt the intestinal microbiota and may influence immune recovery and post-transplant outcomes. However, the impa...